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Dopamine is the hormone responsible for reward-motivation behavior

GSTZ1 deficiency leads to UDP-GlcUA accumulation, stabilizing TGFR1 mRNA by enhancing the interaction between TGFR1 and PTBP3, which in turn activates TGF/Smad signaling and promotes HCC migration [137]

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Currently, several therapies are emerging and undergoing trials in animal models